George Uhl - Recent Papers

Uhl GR, Drgon T, Liu QR, Johnson C, Walther D, Komiyama T, Harano M, Sekine Y, Inada T, Ozaki N, Iyo M, Iwata N, Yamada M, Sora I, Chen CK, Liu HC, Ujike H, Lin SK.Genome-wide association for methamphetamine dependence: convergent results from 2 samples.Arch Gen Psychiatry. 2008 Mar;65(3):345-55.

Drgonova J, Liu QR, Hall FS, Krieger RM, Uhl GR.Deletion of v7-3 (SLC6A15) transporter allows assessment of its roles in synaptosomal proline uptake, leucine uptake and behaviors.Brain Res. 2007 Dec 5;1183:10-20.

Hishimoto A, Liu QR, Drgon T, Pletnikova O, Walther D, Zhu XG, Troncoso JC, Uhl GR.Neurexin 3 polymorphisms are associated with alcohol dependence and altered expression of specific isoforms.Hum Mol Genet. 2007 Dec 1;16(23):2880-91.

Uhl GR, Drgon T, Johnson C, Fatusin OO, Liu QR, Contoreggi C, Li CY, Buck K, Crabbe J."Higher order" addiction molecular genetics: convergent data from genome-wide association in humans and mice.Biochem Pharmacol. 2008 Jan 1;75(1):98-111.

Numachi Y, Ohara A, Yamashita M, Fukushima S, Kobayashi H, Hata H, Watanabe H, Hall FS, Lesch KP, Murphy DL, Uhl GR, Sora I.Methamphetamine-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters.Eur J Pharmacol. 2007 Oct 31;572(2-3):120-8.

Yamamoto H, Kamegaya E, Hagino Y, Imai K, Fujikawa A, Tamura K, Enokiya T, Yamamoto T, Takeshima T, Koga H, Uhl GR, Ikeda K, Sora I.Genetic deletion of vesicular monoamine transporter-2 (VMAT2) reduces dopamine transporter activity in mesencephalic neurons in primary culture.Neurochem Int. 2007 Jul-Sep;51(2-4):237-44.

Uhl GR, Liu QR, Drgon T, Johnson C, Walther D, Rose JE.Molecular genetics of nicotine dependence and abstinence: whole genome association using 520,000 SNPs.BMC Genet. 2007 Apr 3;8:10.

Fukushima S, Shen H, Hata H, Ohara A, Ohmi K, Ikeda K, Numachi Y, Kobayashi H, Hall FS, Uhl GR, Sora I.Methamphetamine-induced locomotor activity and sensitization in dopamine transporter and vesicular monoamine transporter 2 double mutant mice.Psychopharmacology (Berl). 2007 Jul;193(1):55-62.

Job MO, Tang A, Hall FS, Sora I, Uhl GR, Bergeson SE, Gonzales RA.Mu (mu) opioid receptor regulation of ethanol-induced dopamine response in the ventral striatum: evidence of genotype specific sexual dimorphic epistasis.Biol Psychiatry. 2007 Sep 15;62(6):627-34.

Liu QR, Drgon T, Johnson C, Walther D, Hess J, Uhl GR.Addiction molecular genetics: 639,401 SNP whole genome association identifies many "cell adhesion" genes.Am J Med Genet B Neuropsychiatr Genet. 2006 Dec 5;141(8):918-25.

Harburg GC, Hall FS, Harrist AV, Sora I, Uhl GR, Eisch AJ.Knockout of the mu opioid receptor enhances the survival of adult-generated hippocampal granule cell neurons.Neuroscience. 2007 Jan 5;144(1):77-87.

Johnson C, Drgon T, Liu QR, Walther D, Edenberg H, Rice J, Foroud T, Uhl GR.Pooled association genome scanning for alcohol dependence using 104,268 SNPs: validation and use to identify alcoholism vulnerability loci in unrelated individuals from the collaborative study on the genetics of alcoholism.Am J Med Genet B Neuropsychiatr Genet. 2006 Dec 5;141(8):844-53.